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Lengyel, Ernst Robert
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Concept Cell Adhesion
Academic Article The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin.
Academic Article MMP-2 functions as an early response protein in ovarian cancer metastasis.
Academic Article c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion.
Academic Article Loss of E-cadherin promotes ovarian cancer metastasis via alpha 5-integrin, which is a therapeutic target.
Academic Article The Müllerian HOXA10 gene promotes growth of ovarian surface epithelial cells by stimulating epithelial-stromal interactions.
Academic Article {beta}3-integrin expression on tumor cells inhibits tumor progression, reduces metastasis, and is associated with a favorable prognosis in patients with ovarian cancer.
Academic Article Targeting the urokinase plasminogen activator receptor inhibits ovarian cancer metastasis.
Academic Article Use of a novel 3D culture model to elucidate the role of mesothelial cells, fibroblasts and extra-cellular matrices on adhesion and invasion of ovarian cancer cells to the omentum.
Academic Article Transient interaction of activated platelets with endothelial cells induces expression of monocyte-chemoattractant protein-1 via a p38 mitogen-activated protein kinase mediated pathway. Implications for atherogenesis.
Academic Article miR-92a inhibits peritoneal dissemination of ovarian cancer cells by inhibiting integrin a5 expression.
Academic Article Mesothelial cells promote early ovarian cancer metastasis through fibronectin secretion.
Academic Article Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy.
Academic Article The hypoxia-related microRNA miR-199a-3p displays tumor suppressor functions in ovarian carcinoma.
Academic Article Microenvironment-induced downregulation of miR-193b drives ovarian cancer metastasis.
Academic Article Modeling the Early Steps of Ovarian Cancer Dissemination in an Organotypic Culture of the Human Peritoneal Cavity.
Academic Article A High-Throughput Screening Model of the Tumor Microenvironment for Ovarian Cancer Cell Growth.
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